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Packaging of Pharmaceuticals | PHARMACEUTICS-I

Chapter - 4 Packaging of Pharmaceuticals Contents 1. Definition 2. Qualities of Good Container 3. Types of Container 4. Materials Used in Making of Containers 5. Closures 6. Types of Closures 7. Materials Used in Making of Closures 8. Aerosol Packaging 9. Modern Unit Dose Packaging After the manufacturing of drugs, it is essential that these should be stored properly. The stability of drug during its storage depends on so many factors and proper packaging is one of them. The pharmaceutical products are in direct contact with the containers and closures. So improper packing and poor quality of containers may lead to deteriora tion of the products. Pharmaceutical container has been defined as a device that holds the drug and it may or may not be in direct contact with the pharmaceutical preparations. Closures are the devices by means of which containers can be opened and closed. Qualities of a Good Container 1. It should be made of materials which can withstand wear and tear during norma

Introduction To Pharmacopoeia | PHARMACEUTICS-I

Chapter - 2 Introduction To Pharmacopoeia Pharmacological = Pharmakon ( means drug ) + Poesia ( to make ) • Pharmacopoeia is a government official book that describes the standard of drugs, tests of identification, efficacy& potency to be maintained strictly. It contains a collection of monographs published by authorised bodies like the government or pharmaceutical society. • Monograph is a collection of detailed information on a particular drug, chemical name, assay, formula, solubility, identification,  P H  , and dose. Importance of Pharmacopoeia • To maintain uniformity & control the standards of drugs available in the market. • To avoid alteration in drugs • To provide complete information on drugs. • Reference for laboratory, industry and academic instruction. Indian Pharmacopoeia • Indian Pharmacopoeia Commission ( IPC ) set standards for drug manufacturing, sold, and consumption in India. • In pre-independence days, British Pharmacopoeia (BP) was used in India.  • In 1

Size Reduction | PHARMACEUTICS-I

Chapter - 5 Size Reduction Contents 1. Definition 2. Importance of Particle Size Reduction 3. Factors Affecting Size Reduction 4. Methods of Size Reduction  Size reduction or comminution is the process of reducing drugs (vegetable and chemical substances) into smaller pieces, coarse particles or fine powder. Importance of Particle Size Reduction 1. To increase the rate of solution in case of chemical substances, because reduction of the particle size increases the surface area for the action of solvent. 2. To allow the rapid penetration of the solvent (menstruum), in case of crude drugs for the extraction of active constituents from vegetable and animal drugs. 3. To get a uniform powder because particle size reduction helps in uniform mixing of drugs, required for preparing different formulations for administration. 4. To increase the rate of absorption of a drug. The smaller the particle size, the greater is the rate of absorption. 5. To improve the stability of certain pharmaceutica

PHARMACEUTICS-I, MCQs

PHARMACEUTICS-I, MCQs Chapter - 1 Dosage Forms MCQs 1. Select the semi solid dosage form A. Suppository B. Tablet C. Emulsion D. Linctus 2. Select unit dosage form A. Linctus B. Liniment C. Immolation D. Pessaries 3. Dusting powder should pass through sieve number A. 80 B.120 C.160 D. 190 4. Surgical dusting powder should be A. Non irritating B. Sterile C. Free from pathogen D. All of the above 5. One of the main ingredient of dusting powder A. Kaolin B. Tragacanth C. Acacia D. Starch 6. Dusting powders are sterilized by A. Moist heat sterilization B. Dry heat sterilization C. Chemical technique D. Membrane method 7. The abrasive agent used in tooth powders A. Calcium sulphate B. Magnesium carbonate C. Sodium carbonate D. All of the above 8. Effervescent granules contain A. Citric acid B. Ascorbic acid C. Stearic acid D. Calcium carbonate 9. Capsule shell is made up of A. Soft gelatin B. Gelatin   C. Hard gelatin D. Starch 10. What is wrong about pill? A. Disintegration time of pills