RENERVE PLUS INJECTION

                                (ReNerve)
                                                                      PLUS
                                                                      Injection

          Injection of Pyridoxine Hydrochloride,
              Methylcobalamin & Nicotinamide

________________________________________________                                  For IM/IV Us
________________________________________________
COMPOSITION
Each 2ml contains: 
Pyridoxine Hydrochloride IP.                      100mg
Methylcobalamin IP.                               1000mcg
Nicotinamide IP.                                           100mg
Benzyl Alcohol IP.                                         2%w/v
Water For Injection IP.                                       q.s.

pyridoxine Hydrochloride:

• Perhaps the most important of vitamin B's for a healthy body. Pyridoxine Hydrochloride is a master vitamin in the processing of amino acid. The building blocks of all proteins and some hormones. It plays a role in the notification of all cells and the production of red blood cells and the immune system. It also acts as co-enzymes for substances that regulate and stimulate the brain and central nervous system responses.
• Boost immunity
• Protect against cancer and cell abnormalities

It helps control diabetes.

Mecobalamin:

• It is a neurotropic and acts as a growth for nerve cells,  a property that helps to regenerate central & peripheral nervous tissue damaged in disorder such as diabetic peripheral neuropathy.
• Mecobalamin acts as a methyl donor for the synthesis of Lecithin, a major component of the myelin sheath.
• Mecobalamin facilities methylation of t-RNA which plays a fundamental role in protein synthesis and stimulates methionine synthesis and helps to restore normal levels of RNA in nerve cells.
• Mecobalamin acts as a co-factor in the enzyme methionine synthesis which regenerates methionine thus generating an increased supply of S-Adenosyl Methionine(SAMe) and SAMe protects from Neurotoxicity.
• Mecobalamin normalizes nerve cell conduction by healing damaged nerve cells and restores delayed synaptic transmission and diminished neurotransmitter to normal.

Mecobalamin improves the excitability of the nerve fibers and thus improve the neurotransmission.

Nicotinamide:

• Its other name is vitamin B3.
• It is required for cell respiration, helps in the release of energy & metabolism of carbohydrates, fats, and proteins, proper correlation, and healthy skin functioning of the nervous system,   and normal secretion of bile, & stomach fluids.
• It is used in treating schizophrenia and other mental illnesses and a memory enhancer.
• Nicotinic acid given in drug dosage improves the blood cholesterol profile.

A deficiency may cause pellage and is characterized by bilateral dermatitis, diarrhea, and dementia.

INDICATIONS:

1.Neurological Disorders

       a.parkinson's Disease

 b.Alzheimer's Disease

 c.Epilepsy

       d.Facial palsy

2. a.Disturbed functions and memory

    b.Sleep-wake disorders

3. In trauma, Megaloblastic Anaemia caused by vitamin B12 deficiency, cancer, Hyper Homocysteinemia.

DOSAGE: As directed by the physician.

STORAGE: Store at a temperature not exceeding 30-degree.protect from light.

IMPORTANT: Not to be used in newly born babies or premature infants.

_____________________________________